Anti-androgen drugs are used to block the development of male hormones. Are they likely to cause cancer in a person after a long use?
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Anti-androgen drugs are used to block the development of male hormones. Are they likely to cause cancer in a person after a long use?
The side effects of antiandrogens vary depending on the type of antiandrogen – namely whether it is a selective AR antagonist or lowers androgen levels – as well as the presence of off-target activity in the antiandrogen in question. For instance, whereas antigonadotropic antiandrogens like GnRH modulators and cyproterone acetate are associated with pronounced sexual dysfunction and osteoporosis in men, selective AR antagonists like bicalutamide are not associated with osteoporosis and have been associated with only minimal sexual dysfunction.
Anti-androgens can produce a range of side effects, depending on the dose and type you take but cancer isn’t one of them. At least, not that I know of. But some possible side effects include: low sex drive, increased risk of depression, elevated liver enzymes, hepatitis, liver injury, erectile dysfunction, diarrhea, breast tenderness, hot flashes, menstrual irregularity, skin rash, anti-androgen resistance, meaning the medication stops working.